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He was born in 1868 in Moncalvo, a small village in Monferrato, and soon moved with his family to Buenos Aires, where he attended the music courses of Amilcare Zanella, a family friend. Back in Italy, he continued his musical training in Turin.
The Petruzzelli Theater in Bari in a historical photograph
In 1906, his first opera, Velda, a lyrical drama in two acts with a libretto by his brother Giuseppe, a contributor to the newspaper La Stampa, with Angelo Gamba, was performed at the Vittorio Emanuele Theater in the Piedmontese capital. The work received universal critical acclaim and was performed at the Petruzzelli Theater in Bari. In 1910, Alberto Donini, the librettist, performed ''Al mulino'', a lyrical drama in one act, at the same theater in Turin. The work was performed several times, including abroad, and was praised by audiences and critics alike. In 1916, a new work by him was premiered at the Scribe Theater: the Piedmontese dialect operetta ''L'saot dla bela Auda'' with a theme by the dialect actress and writer Gemma Cuniberti and a libretto by Giovanni Drovetti. The response this time was less positive.
The success of the first two works prompted Cassone to embark on the ambitious project of setting ''Il barbiere di Siviglia'', an opera associated with great composers such as Paisiello and Rossini, to music once again. The work, with a libretto by Drovetti, was performed at the Teatro Balbo in Turin in 1922.
The opera was criticized by the press and the drastic verdict jeopardized the career of the Piedmontese composer.
In addition to the works mentioned above, Cassone also wrote several romances, string quartets, other pieces and an opera for voice and piano, Alda, with a libretto by Drovetti, which was never performed.
He died in Turin in 1935 at the age of sixty-six.